Key result
Neutrophil-to-lymphocyte ratio at admission was significantly associated with in-hospital cardiac death, reinfarction, or new-onset heart failure in patients with STEMI (P < .001).
Why the study?
Does the neutrophil-to-lymphocyte ratio (NLR) predict in-hospital cardiac events in patients with ST-segment elevated myocardial infarction?
Observational (n=101)
Does the neutrophil-to-lymphocyte ratio (NLR) predict in-hospital cardiac events in patients with ST-segment elevated myocardial infarction?
The neutrophil-to-lymphocyte ratio at admission is an independent predictor of adverse in-hospital outcomes in patients with STEMI, correlating strongly with the GRACE risk score.
Answers are grounded in this paper and cite their sources.
NLR may aid STEMI risk stratification but should not yet change practice; leaves open incremental value beyond GRACE in prospective validation.
In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P < .001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P < .001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r = .803, P < .001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.
No takes yet. Share an insight, caveat, or question.
Öncel et al. (2013) conducted an observational in ST-segment elevated myocardial infarction (STEMI) (n=101). Neutrophil-to-lymphocyte ratio (NLR) vs. Lower NLR groups was evaluated on In-hospital cardiac death, reinfarction, or new-onset heart failure (p=<.001). Neutrophil-to-lymphocyte ratio at admission was significantly associated with in-hospital cardiac death, reinfarction, or new-onset heart failure in patients with STEMI (P < .001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: