Key result
A high apolipoprotein B to apolipoprotein A-I (apoB/A) ratio was identified as a strong independent prognostic factor for worse overall survival in patients with colorectal cancer (HR 107.07).
Why the study?
The lipid metabolism status of patients with colorectal cancer has not been comprehensively understood.
Cohort (n=231)
No
Hazard Ratio: 107.07 (95% CI 5.75–1993.74)
Absolute Event Rate: 37.1% vs 59.5%
p-value: p=0.002
The apoB/A ratio serves as a strong independent prognostic factor for overall survival in patients with colorectal cancer.
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May refine colorectal cancer prognosis; hypothesis-generating and should not change practice without prospective validation.
Pan et al. (2023) conducted a cohort in Colorectal cancer (n=231). High apolipoprotein B to apolipoprotein A-I (apoB/A) ratio vs. Low apoB/A ratio was evaluated on Overall survival (HR 107.07, 95% CI 5.75-1993.74, p=0.002). A high apolipoprotein B to apolipoprotein A-I (apoB/A) ratio was identified as a strong independent prognostic factor for worse overall survival in patients with colorectal cancer (HR 107.07).
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