Why the study?
Apolipoproteins are implicated in cardiovascular diseases, but the prognostic value of the apolipoprotein B to apolipoprotein A-I ratio in heart failure was unclear.
Does a high serum ApoB/ApoA-I ratio predict mortality in patients with heart failure?
Population
2400 HF patients plus an independent cohort of 838 patients
Comparison
High vs low ApoB/ApoA-I ratio
Design
Cohort study with training, validation, and propensity score-matched cohorts
Authors
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A high serum ApoB/ApoA-I ratio (≥0.69) is an independent predictor of poor prognosis and mortality in patients with heart failure.
Does a high serum ApoB/ApoA-I ratio predict mortality in patients with heart failure?
A high serum ApoB/ApoA-I ratio (≥0.69) is an independent predictor of poor prognosis and mortality in patients with heart failure.
Li et al. (2023) studied this question.
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