November 15, 1993The Journal of Cell BiologyOpen Access

Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.

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Population

Rat skeletal muscle fibers

Design

Preclinical

Authors

CDCelise DenardiDuke Medical Center SASimonetta AusoniUniversity of Padua PMPaolo MorettiIstituto Giannina Gaslini

Discussion

Member takes

Implication

2X-MyHC arises from a distinct gene in rat muscle; leaves open whether analogous regulation applies in human cardiac or skeletal disease.

Structured PICO

Population

Rat skeletal muscle fibers

Intervention

Isolation and characterization of cDNAs coding 2X-MyHC

Outcome

Identification of 2X-MyHC as a product of a distinct gene and its expression pattern

The 2X-myosin heavy chain isoform in rat skeletal muscle is coded by a distinct, developmentally regulated gene rather than being a posttranslational modification.

Cite This Study

Denardi et al. (1993) studied this question.

synapsesocial.com/papers/6a81b2aeebcdd2e0baf1f988 https://doi.org/10.1083/jcb.123.4.823

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Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider