Key result
Leadless pacemaker implantation alongside an existing ICD lead resolves diaphragmatic stimulation with stable parameters.
Why the study?
Does implanting a leadless pacemaker alongside an existing transvenous ICD lead safely resolve pacing-induced diaphragmatic stimulation and allow beta-blocker optimization in a patient with bilateral subclavian vein occlusion?
Case Report (n=1)
No
Does implanting a leadless pacemaker alongside an existing transvenous ICD lead safely resolve pacing-induced diaphragmatic stimulation and allow beta-blocker optimization in a patient with bilateral subclavian vein occlusion?
Concomitant implantation of a leadless pacemaker alongside a pre-existing transvenous ICD lead is a feasible and effective strategy to manage pacing-induced diaphragmatic stimulation when bilateral subclavian vein occlusion and prior infection preclude lead extraction or revision.
Answers are grounded in this paper and cite their sources.
May offer an alternative for diaphragmatic stimulation in complex ICD cases with vein occlusion; leaves open prospective validation before broader adoption.
A 75-year-old woman received a single-chamber implantable cardioverter-defibrillator (ICD) 20 years ago after experiencing a syncopal episode. She had frequent premature ventricular contractions (PVCs) without any conduction electrical system disorders (Figure 1A), preserved left ventricular function, no significant valvular disease, and normal coronary arteries. An electrophysiological study revealed reproducible syncopal ventricular tachycardia with the same morphology as the PVCs. Owing to a pocket infection, the left-sided system was removed with complete transvenous lead extraction, and subsequently a new ICD was implanted on the right side after reassessment of the indication.
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Segreti et al. (2024) conducted a case report in Implantable cardioverter-defibrillator (ICD) carrier with reproducible diaphragmatic stimulation, bilateral subclavian vein occlusion, and history of pocket infection (n=1). Leadless pacemaker implantation (Micra TPS) alongside existing transvenous ICD lead, combined with transition from low-dose bisoprolol to high-dose metoprolol was evaluated on Resolution of diaphragmatic stimulation symptoms, pacing parameters, and reduction of PVC burden and ICD therapies. Leadless pacemaker implantation alongside an existing transvenous ICD lead resolved diaphragmatic stimulation with stable pacing (0.38 V at 0.24 ms) and sensing (8 mV) without acute complications.
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