Why the study?
Does systemically administered tempol reduce central neuronal activity in cardiovascular presympathetic regions of the brain in rats?
Does systemically administered tempol reduce central neuronal activity in cardiovascular presympathetic regions of the brain in rats?
Systemically administered tempol reduces blood pressure and sympathetic nerve activity by acting upon neurons in the paraventricular nucleus and rostral ventrolateral medulla, likely by reducing reactive oxygen species.
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Supports central sympathoinhibitory action of systemic tempol in rats; leaves open translation to human hypertension.
Wei et al. (2009) studied this question.
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