Why the study?
Does tempol reduce sympathetic nerve activity and blood pressure in DOCA-salt rats?
Does tempol reduce sympathetic nerve activity and blood pressure in DOCA-salt rats?
Tempol-induced depressor responses are mediated largely by NO-independent sympathoinhibition in sham and DOCA-salt rats.
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Tempol's sympathoinhibitory effects merit exploration in salt-sensitive hypertension models; leaves open clinical translation pending human data.
Xu et al. (2002) studied this question.
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