June 21, 2011IEEE Transactions on Biomedical Engineering

Multiscale Entropy Analysis of Pulse Wave Velocity for Assessing Atherosclerosis in the Aged and Diabetic

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Why the study?

Does multiscale entropy analysis of pulse wave velocity improve the assessment of atherosclerosis in aged and diabetic populations compared to conventional parameters?

Population

91 subjects from a single medical institution, divided into four groups: young healthy adults, healthy upper…

Comparison

Large-scale multiscale entropy index of pulse… vs Conventional parameter of PWV and multiscale…

Design

Cross-sectional

Authors

HWHsien–Tsai WuCentral South University PHPo-Chun Hsu CLCheng‐Feng LinUniversity of Illinois Urbana-Champaign

Discussion

Member takes

Implication

MEI(LS) may refine atherosclerosis assessment in aging and diabetes; hypothesis-generating and requires prospective validation before clinical adoption.

Structured PICO

Does multiscale entropy analysis of pulse wave velocity improve the assessment of atherosclerosis in aged and diabetic populations compared to conventional parameters?

Population

91 subjects from a single medical institution, divided into four groups: young healthy adults (n=22), healthy upper middle-aged adults (n=28), type 2 diabetics with satisfactory blood sugar control (n=21), and type 2 diabetics with unsatisfactory blood sugar control (n=20).

Intervention

Large-scale multiscale entropy index of pulse wave velocity (MEI(LS) (PWV)) derived from 1000 successive recordings within 30 minutes using a self-developed six-channel ECG-PWV-based equipment.

Comparator

Conventional parameter of PWV(foot) and multiscale entropy index on R-R interval (MEI(RRI)).

Outcome

Differentiation of the degree of atherosclerotic change between age groups and glycemic control groups.surrogate

Multiscale entropy analysis of pulse wave velocity provides a dynamic parameter that better reflects the impact of age and glycemic control on atherosclerosis progression compared to conventional static parameters.

Cite This Study

Wu et al. (2011) studied this question.

synapsesocial.com/papers/6a81d899080e7f4ac74d7d13 https://doi.org/10.1109/tbme.2011.2159975

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Implication

MEI(LS) may refine atherosclerosis assessment in aging and diabetes; hypothesis-generating and requires prospective validation before clinical adoption.

Multiscale Entropy Analysis of Pulse Wave Velocity for Assessing Atherosclerosis in the Aged and Diabetic

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Multiscale Entropy Analysis of Pulse Wave Velocity for Assessing Atherosclerosis in the Aged and Diabetic

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider