Why the study?
Does beta-blocker therapy reduce left ventricular hypertrophy in patients with Takayasu arteritis and moderate or severe aortic regurgitation?
Population
20 Japanese women with Takayasu arteritis complicated by moderate or severe aortic regurgitation, mean age…
Comparison
Long-term therapeutic doses of beta-blockers… vs Standard anti-hypertensive therapy without…
Design
Cohort
Follow-up
mean 7.0 +/- 2.0 years
Authors
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May support beta-blockers to stabilize LV mass in Takayasu arteritis with AR; hypothesis-generating, needs randomized confirmation.
Does beta-blocker therapy reduce left ventricular hypertrophy in patients with Takayasu arteritis and moderate or severe aortic regurgitation?
Beta-blocker therapy can safely slow or reverse the progression of left ventricular hypertrophy in patients with Takayasu arteritis and moderate to severe aortic regurgitation without worsening clinical status or LV function.
Gustavo et al. (2000) studied this question.
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