June 29, 2017Diabetes CareOpen Access

Computed Tomography Angiography Images of Coronary Artery Stenosis Provide a Better Prediction of Risk Than Traditional Risk Factors in Asymptomatic Individuals With Type 2 Diabetes: A Long-term Study of Clinical Outcomes

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Why the study?

Does CCTA-detected obstructive CAD improve the prediction of MACE compared to traditional risk factors in asymptomatic patients with type 2 diabetes?

Population

933 asymptomatic patients with type 2 diabetes who underwent coronary computed tomography angiography (CCTA)

Comparison

Coronary computed tomography angiography to… vs Traditional risk factors alone or coronary…

Design

Cohort

Follow-up

mean 5.5 ± 2.1 years

Authors

KLKwan Yong LeeSt. Mary's Hospital BHByung‐Hee HwangSt. Mary's Hospital TKTae‐Hoon KimChungbuk National University

Discussion

Member takes

Implication

Draft 2:* Routine CCTA screening may refine risk stratification in asymptomatic T2.

Structured PICO

Does CCTA-detected obstructive CAD improve the prediction of MACE compared to traditional risk factors in asymptomatic patients with type 2 diabetes?

Population

933 asymptomatic patients with type 2 diabetes who underwent coronary computed tomography angiography (CCTA)

Intervention

Coronary computed tomography angiography (CCTA) to detect obstructive coronary artery disease (≥50% stenosis)

Comparator

Traditional risk factors alone (age, male, hypertension, hyperlipidemia, smoking, estimated glomerular filtration rate, and HbA1c) or coronary artery calcium score

Outcome

Major adverse cardiovascular events (MACE), including all-cause mortality, nonfatal myocardial infarction, and late coronary revascularizationcomposite

CCTA-detected obstructive CAD significantly improves long-term MACE risk prediction beyond traditional risk factors in asymptomatic patients with type 2 diabetes.

Cite This Study

Lee et al. (2017) studied this question.

synapsesocial.com/papers/6a8201106494b7aed7bf7ec4 https://doi.org/10.2337/dc16-1844

Topics

Coronary artery disease Statin therapy Coronary CT angiography

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Computed Tomography Angiography Images of Coronary Artery Stenosis Provide a Better Prediction of Risk Than Traditional Risk Factors in Asymptomatic Individuals With Type 2 Diabetes: A Long-term Study of Clinical Outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Computed Tomography Angiography Images of Coronary Artery Stenosis Provide a Better Prediction of Risk Than Traditional Risk Factors in Asymptomatic Individuals With Type 2 Diabetes: A Long-term Study of Clinical Outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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