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June 24, 2020ESC Heart FailureOpen Access

The Impact of Left Ventricular Diastolic Dysfunction for the Prognosis in Patients with Lower Extremity Arterial Disease

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Why the study?

The characteristics of left ventricular diastolic dysfunction and its association with prognosis in patients with lower extremity arterial disease had not been fully examined.

Population

464 LEAD patients and 221 controls from outpatient clinics and hospitals

Comparison

Different grades of LVDD severity

Design

Consecutive observational cohort study

Authors

JLJen‐Kuang LeeNational Taiwan UniversityJHJuey‐Jen HwangInterventional CardiologyFCFu‐Tien ChiangElectrophysiology

Discussion

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Implication

LVDD may aid risk stratification in LEAD; hypothesis-generating and requires prospective validation before practice change.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Lee et al. (2020) studied this question.

synapsesocial.com/papers/6a8216a0d96cdbb40a9cd1d3https://doi.org/10.1002/ehf2.12839

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of left ventricular diastolic dysfunction in European populations based on cross-validated diagnostic thresholds2012 · 86 citations
  2. 2Prognostic significance of polyvascular disease in heart failure with preserved left ventricular ejection fraction2019 · 18 citations
  3. 3Peripheral artery disease and risk of adverse outcomes in heart failure with preserved ejection fraction2017 · 24 citations
  4. 4Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging2016 · 2,510 citations
  5. 5Plasma levels of tumor necrosis factor-α and interleukin-6 are associated with diastolic heart failure through downregulation of sarcoplasmic reticulum Ca2+ ATPase2011 · 123 citations