Barriers to medication adherence and links to cardiovascular disease risk factor control: the Framingham Heart Study
Why the study?
Does low medication adherence worsen cardiovascular disease risk factor control in older adults?
Population
1,559 older participants with hypertension, dyslipidaemia, and diabetes from the Framingham Heart Study…
Comparison
Low medication adherence vs High medication adherence (score <2)
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports adherence assessment in older adults; leaves open whether interventions improve BP or LDL control.
Structured PICO
Does low medication adherence worsen cardiovascular disease risk factor control in older adults?
P
Population
1,559 older participants with hypertension, dyslipidaemia, and diabetes from the Framingham Heart Study, median age 70 years, 53% women.
I
Intervention
Low medication adherence (score ≥2 on the four-item Morisky Medication Adherence Scale)
C
Comparator
High medication adherence (score <2)
O
Outcome
Levels of cardiovascular disease risk factors (diastolic blood pressure, low-density lipoprotein cholesterol, fasting plasma glucose, haemoglobin A1c)surrogate
Depressive symptoms are associated with lower medication adherence, which in turn is linked to poorer control of blood pressure and LDL cholesterol in older adults.
Cite This Study
Hwang et al. (2017) studied this question.