Case report demonstrates rapid fibrin clot dissolution following intracameral r-TPA in postoperative endophthalmitis, highlighting its potential utility in refractory ocular inflammation.
INTRODUCTION: The aim of this paper was to describe the use of r-TPA for fibrin clot dissolution following endophthalmitis. CLINICAL PICTURE: A 74-year-old man presented with painful loss of vision following routine uncomplicated cataract surgery. TREATMENT: He underwent standard treatment for postoperative endophthalmitis but despite this, developed a dense fibrin clot. He underwent further intracameral injection of r-TPA. OUTCOME: Following the injection, he had complete clot dissolution within 2 hours without any complications. CONCLUSION: R-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery.
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Riaz et al. (2006) studied this question.
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