Postpolypectomy Syndrome in a Case of Colocolic Intussusception

Colorectal polyps are common and are routinely managed with colonoscopic polypectomy. Postpolypectomy syndrome (PPS) is a rare but recognized complication following hot snare polypectomy (HSP), caused by a transmural burn without frank perforation. It mimics colonic perforation clinically but is managed conservatively. We report a 50-year-old woman with colocolic intussusception secondary to a large pedunculated sigmoid polyp. Following HSP, she developed fever and abdominal pain, with computed tomography imaging suggestive of PPS. PPS should be considered in postpolypectomy patients with abdominal pain and fever without radiological evidence of perforation. Awareness of this condition prevents unnecessary laparotomy.