Population
Prototype coxsackievirus B4 preparations and a variant that produced diabetes in mice
Comparison
Characterization of protein kinase activity vs Diabetogenic variant of coxsackievirus B4
Design
Preclinical
Authors
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Should not alter clinical management of coxsackievirus infections; hypothesis-generating for protein kinase role in diabetogenic variants.
Identifies a protein kinase in nondiabetogenic coxsackievirus B4 that is absent in a diabetogenic variant, suggesting a potential role in viral pathogenesis.
Chatterjee et al. (1986) studied this question.
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