November 5, 2024Journal of obstetrics and gynaecology researchOpen Access

Clinical implications of genetic testing for congenital protein C deficiency in pregnancy

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Population

Two cases of deep vein thrombosis diagnosed during pregnancy

Design

Case report

Authors

TMTomoka MaehanaBeijing Obstetrics and Gynecology Hospital TNToshiya NishikuboJapanese Red Cross Narita Hospital RMRyo MaekawaYamaguchi University

Discussion

Member takes

Implication

May support targeted testing for protein C deficiency in select pregnant DVT cases; leaves open validation in prospective cohorts before broader adoption.

Structured PICO

Population

2 pregnant patients with deep vein thrombosis

Intervention

Genetic testing for congenital protein C deficiency

Outcome

Confirmation of congenital protein C deficiency via genetic mutation identification

Genetic testing for congenital protein C deficiency in pregnant women with DVT facilitates tailored postpartum management and early intervention for newborns.

Cite This Study

Maehana et al. (2024) studied this question.

synapsesocial.com/papers/6a82272379a2afcf14ffae6b https://doi.org/10.1111/jog.16138

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Implication

May support targeted testing for protein C deficiency in select pregnant DVT cases; leaves open validation in prospective cohorts before broader adoption.

Clinical implications of genetic testing for congenital protein C deficiency in pregnancy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Clinical implications of genetic testing for congenital protein C deficiency in pregnancy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider