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January 27, 2004HypertensionOpen Access

Cardiovascular Risk Factors and Sequelae in Hypertensive Children Identified by Referral Versus School-Based Screening

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Why the study?

Do cardiovascular risk factors and surrogate markers of hypertensive injury differ between hypertensive children identified by referral versus school-based screening?

Population

97 hypertensive children

Comparison

Identification by referral from primary care… vs Identification through community-based school…

Design

Cross-sectional, Echocardiography reviewed by 2 independent sonographers…

Authors

JSJonathan M. SorofGlobal Blood Therapeutics (United States)JTJennifer TurnerBrigham and Women's HospitalDMDavid S. MartinKBR (United States)

Discussion

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Implication

LVH excess in referred vs screened hypertensive youth is BMI-mediated; hypothesis-generating for obesity as primary driver of early cardiac remodeling.

Structured PICO

Do cardiovascular risk factors and surrogate markers of hypertensive injury differ between hypertensive children identified by referral versus school-based screening?

P
Population
97 hypertensive children (54 identified during school screening of 5,102 students in Houston public schools, and 43 referred to a hypertension clinic for persistently elevated blood pressure)
I
Intervention
Identification by referral from primary care providers
C
Comparator
Identification through community-based school screening
O
Outcome
Cardiovascular risk factors and surrogate markers of hypertensive injury (left ventricular mass index, prevalence of left ventricular hypertrophy, carotid intimal-medial thickness)surrogate

Hypertensive children identified by referral exhibit more severe surrogate markers of cardiovascular disease than those identified by screening, but this difference is primarily driven by a higher BMI in referred patients.

Cite This Study

Sorof et al. (2004) studied this question.

synapsesocial.com/papers/6a822be1f337522b6774abc4https://doi.org/10.1161/01.hyp.0000114696.96318.4e

Topics

Hypertension managementWomen and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac Status in Juvenile Borderline Hypertension1983 · 114 citations
  2. 2Left ventricular hypertrophy in children with blood pressures in the upper quintile of the distribution. The Muscatine Study.1981 · 127 citations
  3. 3Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents: A Working Group Report from the National High Blood Pressure Education Program1996 · 999 citations
  4. 4Ambulatory Blood Pressure and Left Ventricular Mass Index in Hypertensive Children2002 · 317 citations
  5. 5Carotid Artery Intimal-Medial Thickness and Left Ventricular Hypertrophy in Children With Elevated Blood Pressure2003 · 390 citations