Why the study?
Low resting heart rate and premature atrial contractions predict incident AF and could be interdependent, but their combined association with incident AF needed investigation.
Do low mean heart rate and increased supraventricular activity on 24hECG independently predict incident atrial fibrillation in AF-free subjects?
Population
377 AF-free subjects in the Malmö Diet and Cancer study
Comparison
Different levels of mean heart rate and supraventricular activity at 24hECG
Design
Prospective population-based cohort study
Follow-up
Mean 17 years
Authors
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May aid AF risk stratification on 24h ECG; leaves open whether markers warrant targeted prevention trials.
Do low mean heart rate and increased supraventricular activity on 24hECG independently predict incident atrial fibrillation in AF-free subjects?
Low mean heart rate and increased supraventricular activity on 24-hour ECG independently predict incident atrial fibrillation, with their combination identifying a high-risk subgroup.
Persson et al. (2019) studied this question.
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