Phytochemical investigation and in vitro anti-diabetic activity of Terminalia Catappa leaves

Alpha-glucosidases and alpha-amylases play the crucial role in the carbohydrate digestion. The inhibition of these enzymes may be effective in retarding glucose absorption and it can be effectively implement for the management of blood glucose. Conventional knowledge of medicinal plants has constantly guided the search for new cures. In this study we investigate the in vitro anti-diabetic effects of methanolic extract of Terminalia Catappa . The extract exhibit the dosage-dependent increase in inhibitory effect on alpha-glucosidase enzyme (upto 73.2%), and alpha-amylase enzyme (upto 54.04%). The current study supports that the in vitro anti-diabetic activity of methanolic extract of T. catappa leaves. Further, in vivo studies are warranted to confirm the anti-diabetic potentials of T. catappa .