Why the study?
The authors sought to examine the scientific evidence supporting The Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S) syndromes.
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Design
Review
RED-S lacks support for clinical use in athletes; leaves open its validity as a syndrome pending rigorous prospective research.
We examine the scientific evidence supporting The Female Athlete Triad and Relative Energy Deficiency in Sport (RED-S) syndromes. More research is necessary to advance the understanding of both syndromes; however, it is premature to consider RED-S as an evidence-based syndrome. Future research should specifically define RED-S components, determine its clinical relevance, and establish the causality of relative energy deficiency on RED-S outcomes.
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Williams et al. (2019) studied this question.
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