Palladium(II)‐Catalyzed Selective Monofluorination of Benzoic Acids Using a Practical Auxiliary: A Weak‐Coordination Approach

This is the authors' abstract. We don't add key points for this paper.

Finally, a choice! A highly selective palladium(II)-catalyzed ortho-monofluorination reaction has been achieved for the first time through a weak coordination (see scheme; Ar=2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl). Simple modification of this protocol allows for a choice between mono- and difluorination. The mono- and difluorinated benzoic acid derivatives are valuable in the pharmaceutical and agrochemical industries.