January 31, 2025Physician s Journal of MedicineOpen Access

Association Between Gallbladder Surgery and Congestive Heart Failure: A Population-Based Cross-Sectional Analysis Using NHANES Data

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Why the study?

Given shared risk factors between gallbladder disease and congestive heart failure, this study investigated whether a history of gallbladder surgery is associated with a higher prevalence of CHF.

Does a history of gallbladder surgery increase the odds of congestive heart failure in adults?

Population

7,800 adults aged ≥20 years in NHANES

Comparison

History of gallbladder surgery vs no history of gallbladder surgery

Design

Population-based cross-sectional analysis

Authors

EAEsther AuerbachState University of New York SHShmuel HalpertJersey Shore University Medical Center YFYaacov FakiroTouro University Nevada

Discussion

Member takes

Implication

Gallbladder surgery history may flag elevated CHF risk; leaves open causality and needs prospective validation before clinical use.

Structured PICO

Does a history of gallbladder surgery increase the odds of congestive heart failure in adults?

Population

7,800 adults aged ≥20 years from the National Health and Nutrition Examination Survey (NHANES) with complete data on gallbladder surgery history and congestive heart failure diagnosis.

Intervention

History of gallbladder surgery (self-reported, used as a proxy for gallbladder disease)

Comparator

No history of gallbladder surgery

Outcome

Self-reported provider diagnosis of congestive heart failure (CHF)hard clinical

A history of gallbladder surgery is associated with nearly twice the odds of congestive heart failure, suggesting that gallbladder disease may serve as an early marker of cardiovascular risk.

Limitations

Cross-sectional nature precludes determination of causality
Use of gallbladder surgery history as a proxy does not fully capture disease spectrum or severity
Self-reported CHF and surgery may introduce recall or reporting bias
Potential for residual confounding from unmeasured factors (e.g., genetics, obesity, diet, medications)
NHANES data may limit external validity to other populations
Does not investigate biological processes accounting for the association

Cite This Study

Auerbach et al. (2025) studied this question.

synapsesocial.com/papers/6a8244e344e83484cc93b482 https://doi.org/10.55070/001c.134095

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Association Between Gallbladder Surgery and Congestive Heart Failure: A Population-Based Cross-Sectional Analysis Using NHANES Data

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Association Between Gallbladder Surgery and Congestive Heart Failure: A Population-Based Cross-Sectional Analysis Using NHANES Data

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider