Why the study?
Does the APOAV (T-1131C) polymorphism rare allele affect plasma triglyceride and lipoprotein cholesterol levels in dyslipidemic and control populations?
Population
Three dyslipidemic populations and a control population across Chinese, Hispanic, and European ethnic groups
Comparison
Possession of the rare allele of the APOAV… vs Non-possession of the rare allele
Design
Cross-sectional
Authors
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Rare APOAV allele linked to adverse lipids in cross-sectional data; hypothesis-generating for CV risk, needs prospective validation.
Does the APOAV (T-1131C) polymorphism rare allele affect plasma triglyceride and lipoprotein cholesterol levels in dyslipidemic and control populations?
The APOAV (T-1131C) polymorphism rare allele is associated with elevated plasma triglycerides and VLDL cholesterol, suggesting it is an important determinant of lipid profiles and a potential cardiovascular risk factor.
Aouizerat et al. (2003) studied this question.
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