Heart Failure Re-admission and Mortality in Chronic Kidney Disease Patients after Transcatheter AorticValve Replacement in Asian Population

Ryo Yamaguchi; Masanori Yamamoto; Tetsuro Shimura; Yuya Adachi; Ai Kagase; Takahiro Tokuda; Satoshi Tsujimoto; Yutaka Koyama; Toshiaki Otsuka; Fumiaki Yashima; Yusuke Watanabe; Norio Tada; Toru Naganuma; Motoharu Araki; Futoshi Yamanaka; Kazuki Mizutani; Minoru Tabata; Hiroshi Ueno; Kensuke Takagi; Shinichi Shirai; Kentaro Hayashida

doi:10.33290/jtvt.oa.22-0004

Why the study?

Chronic kidney disease increases the risk of cardiorenal events, but the rates of late adverse cardiorenal events among patients with CKD following TAVR required assessment.

Does advanced chronic kidney disease increase the risk of mortality and heart failure readmission in patients undergoing transcatheter aortic valve replacement?

Structured PICO

Does advanced chronic kidney disease increase the risk of mortality and heart failure readmission in patients undergoing transcatheter aortic valve replacement?

P

Population

2,588 patients who underwent transcatheter aortic valve replacement (TAVR) from the OCEAN-TAVI multicenter registry in Japan, mean age 84.4 years. Patients were categorized by baseline Chronic Kidney Disease (CKD) stages.

I

Intervention

Transcatheter aortic valve replacement (TAVR)

C

Comparator

Comparison across different baseline Chronic Kidney Disease (CKD) stages (1+2, 3a, 3b, 4, and 5)

O

Outcome

Impact of baseline CKD stages on all-cause death, cardiorenal (CR) death, and non-CR death, and the impact of risk factors of rehospitalization for heart failure (re-HF) within 1 year on mortalityhard clinical

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Implication

In patients undergoing TAVR, advanced chronic kidney disease is independently associated with a significantly increased risk of heart failure readmission and cardiorenal mortality within 1 year.

Abstract

Objective: Chronic kidney disease (CKD) increases the risk of cardiorenal (CR) events such as progression leading to regular hemodialysis, rehospitalization for heart failure (re-HF), and death from cardiac or renal cause (CR death). This study aimed to assess the rates of late adverse CR events among patients with CKD following transcatheter aortic valve replacement (TAVR).

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Cite This Study

Yamaguchi et al. (2022) studied this question.

synapsesocial.com/papers/6a82473780b3939dcdca3b9c https://doi.org/10.33290/jtvt.oa.22-0004

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Heart Failure Re-admission and Mortality in Chronic Kidney Disease Patients after Transcatheter AorticValve Replacement in Asian Population

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Heart Failure Re-admission and Mortality in Chronic Kidney Disease Patients after Transcatheter AorticValve Replacement in Asian Population

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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