Relationship between Mediterranean diet and time in therapeutic range in atrial fibrillation patients taking vitamin K antagonists
Why the study?
Does adherence to a Mediterranean diet affect time in therapeutic range in non-valvular atrial fibrillation patients taking vitamin K antagonists?
Population
553 non-valvular atrial fibrillation patients treated with oral vitamin K antagonists
Comparison
Adherence to Mediterranean diet vs Lower adherence to Mediterranean diet
Design
Cohort
Follow-up
median 31.6 months
Authors
Discussion
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Member takes
Implication
Mediterranean diet adherence was associated with fewer events without worsening TTR in VKA-treated AF; hypothesis-generating and requires randomized confirmation.
Structured PICO
Does adherence to a Mediterranean diet affect time in therapeutic range in non-valvular atrial fibrillation patients taking vitamin K antagonists?
P
Population
553 non-valvular atrial fibrillation patients treated with oral vitamin K antagonists
I
Intervention
Adherence to Mediterranean diet (assessed via validated nine-item dietary questionnaire)
C
Comparator
Lower adherence to Mediterranean diet (compared across tertiles of Med-Diet score)
O
Outcome
Time in therapeutic range (TTR)surrogate
Adherence to a Mediterranean diet does not negatively impact time in therapeutic range for AF patients on VKAs and is associated with a reduction in cardiovascular events.
Cite This Study
Pignatelli et al. (2015) studied this question.