January 1, 2010Internal MedicineOpen Access

Short-Term Case Fatality Rate and Associated Factors among Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 15-Year Period

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Population

1,083 inpatients admitted to a teaching hospital in Taiwan between 1991 and 2005.

Design

Cohort

Follow-up

28 days

Authors

HCHua-Fen ChenFu Jen Catholic University CWChih‐Yuan WangNational Sun Yat-sen University HLHsinyu LeeNational Taiwan University

Discussion

Member takes

Implication

Pneumonia signals elevated 28-day mortality in DKA/HHS; leaves open whether comorbidity-targeted interventions improve survival.

Structured PICO

Population

1,083 inpatients (689 with diabetic ketoacidosis [DKA] and 394 with hyperglycemic hyperosmolar state [HHS]) admitted to a teaching hospital in Taiwan between 1991 and 2005.

Outcome

28-day case-fatality ratehard clinical

While 28-day case-fatality rates for DKA and HHS improved over a 15-year period, comorbidities such as pneumonia, stroke, and myocardial infarction remain significant predictors of mortality.

Limitations

Small sample size for certain subgroups (e.g., myocardial infarction cases, deceased individuals in reference groups)
Random variation in relative risk estimates after sample size attrition
Reduced statistical power in separate analyses according to primary and secondary diagnoses

Cite This Study

Chen et al. (2010) studied this question.

synapsesocial.com/papers/6a8247bc47f72330e2ffb836 https://doi.org/10.2169/internalmedicine.49.2965

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January 1, 2010Internal MedicineOpen Access

Short-Term Case Fatality Rate and Associated Factors among Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 15-Year Period

View Full Paper

Ask AI

Bookmark

Population

1,083 inpatients admitted to a teaching hospital in Taiwan between 1991 and 2005.

Design

Cohort

Follow-up

28 days

Authors

HCHua-Fen ChenFu Jen Catholic University CWChih‐Yuan WangNational Sun Yat-sen University HLHsinyu LeeNational Taiwan University

Discussion

Member takes

Implication

Pneumonia signals elevated 28-day mortality in DKA/HHS; leaves open whether comorbidity-targeted interventions improve survival.

Structured PICO

Population

1,083 inpatients (689 with diabetic ketoacidosis [DKA] and 394 with hyperglycemic hyperosmolar state [HHS]) admitted to a teaching hospital in Taiwan between 1991 and 2005.

Outcome

28-day case-fatality ratehard clinical

While 28-day case-fatality rates for DKA and HHS improved over a 15-year period, comorbidities such as pneumonia, stroke, and myocardial infarction remain significant predictors of mortality.

Limitations

Small sample size for certain subgroups (e.g., myocardial infarction cases, deceased individuals in reference groups)
Random variation in relative risk estimates after sample size attrition
Reduced statistical power in separate analyses according to primary and secondary diagnoses

Cite This Study

Chen et al. (2010) studied this question.

synapsesocial.com/papers/6a8247bc47f72330e2ffb836 https://doi.org/10.2169/internalmedicine.49.2965

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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