Why the study?
Does a high AST/ALT ratio predict cardiovascular mortality and elevated BNP in the general population?
Population
3,494 Japanese subjects from the general population who participated in a community-based health check-up
Comparison
High AST/ALT ratio (>90 percentile) vs Lower AST/ALT ratio (≤90 percentile)
Design
Cohort
Follow-up
10 years
Authors
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May support mortality risk stratification via routine labs; leaves open added value beyond standard models.
Does a high AST/ALT ratio predict cardiovascular mortality and elevated BNP in the general population?
The AST/ALT ratio, a simple and cost-effective marker routinely measured during health check-ups, is predictive of cardiovascular mortality and associated with elevated BNP in the general population.
Yokoyama et al. (2016) studied this question.
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