Why the study?
Does nifedipine retard compared to ACE inhibitors prevent the progression of coronary atherosclerosis?
Population
Patients with coronary atherosclerosis
Comparison
Nifedipine retard over a 3-year treatment… vs Angiotensin-converting enzyme inhibitors over a…
Design
Cohort
Follow-up
3 years
Authors
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Suggests calcium channel blockade may attenuate angiographic coronary atherosclerosis progression compared to ACE.
Does nifedipine retard compared to ACE inhibitors prevent the progression of coronary atherosclerosis?
Nifedipine retard was more effective than ACE inhibitors in suppressing the angiographic progression of mild to moderate coronary atherosclerosis over 3 years.
Shinoda et al. (2005) studied this question.
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