Why the study?
Does early prehypertension compared to late prehypertension increase the risk of adverse obstetrical outcomes in pregnant women?
Does early prehypertension compared to late prehypertension increase the risk of adverse obstetrical outcomes in pregnant women?
Early prehypertension (<20 weeks) in pregnancy is associated with a significantly higher risk of pregnancy-related hypertension and composite adverse outcomes compared to late prehypertension or normotension.
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Suggests early gestational blood pressure elevations may warrant closer monitoring; leaves open whether targeted.
INTRODUCTION: Hypertensive disorders play a significant role in maternal morbidity and mortality. Limited data on prehypertension (preHTN) in pregnancy exist. We examine the risk of adverse outcomes in patients with preHTN in early (<20 weeks) versus late pregnancy (>20 weeks). MATERIALS AND RESULTS: There were 125 control, 95 early preHTN, 136 late preHTN, and 21 chronic hypertension (CHTN). Early preHTN had an increased risk of pregnancy-related hypertension (PRH) (OR 12.26, p < .01) and composite adverse outcomes (OR 2.32, p < .01). Late preHTN had an increased risk for PRH (OR 4.39, p = .02) compared with normotensive and decreased risk for PRH (OR 0.26, p = .02), and composite adverse outcomes (OR 0.379, p = .04) compared with CHTN. Compared with late preHTN, early preHTN had more PRH (OR 2.85, p < .01), and composite adverse outcomes (OR 1.68, p = .04). CONCLUSIONS: Early prehypertension increases the risk of adverse obstetrical outcomes. Other than an increased risk of PRH, patients with late prehypertension have outcomes similar to normotensive women.
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Rosner et al. (2017) studied this question.
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