Why the study?
Does exercise training alter the effect of chronic hypoxia on myocardial adrenergic and muscarinic receptor number in rats?
Population
Rats (four groups: normoxic sedentary, normoxic training, hypoxic sedentary, hypoxic training)
Comparison
Exercise training in hypoxia vs Sedentary rats in hypoxia, and normoxic controls
Design
Preclinical
Follow-up
10 weeks
Authors
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Hypothesis-generating in rat hypoxia models; clinical translation and human relevance remain untested.
Does exercise training alter the effect of chronic hypoxia on myocardial adrenergic and muscarinic receptor number in rats?
Exercise training in hypoxia prevents right ventricular hypertrophy and attenuates hypoxia-induced changes in myocardial adrenergic and muscarinic receptor densities in a rat model.
Favret et al. (2001) studied this question.
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