Population
19 heterozygous female patients with 25 adrenocortical tumours
Design
Case_series
Authors
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May aid differentiation of adrenocortical tumors; leaves open whether polyclonality predicts adenoma behavior.
Adrenocortical carcinomas are monoclonal, whereas adenomas exhibit genetic heterogeneity, suggesting they may arise from single or multiple cells.
Gicquel et al. (1994) studied this question.
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