Why the study?
Is elevated location-specific epicardial adipose tissue thickness associated with obstructive coronary artery disease?
Population
10 observational studies pooling 1,625 subjects with suspicion of CAD or at high risk of CAD clinically.
Comparison
Elevated location-specific epicardial adipose… vs Non-CAD group.
Design
Meta-analysis
Authors
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May support left AV groove EAT as CAD biomarker; extends observational data but requires prospective validation.
Is elevated location-specific epicardial adipose tissue thickness associated with obstructive coronary artery disease?
Elevated location-specific epicardial adipose tissue thickness at the left atrioventricular groove is significantly associated with obstructive coronary artery disease and may serve as a useful imaging biomarker for CAD risk stratification.
Wu et al. (2014) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: