Why the study?
Does rivaroxaban prevent recurrence or aggravation of symptomatic VTE in Japanese patients with venous thromboembolism?
Population
1,039 Japanese patients with acute DVT or PE prescribed rivaroxaban
Comparison
Rivaroxaban treatment (patients with DVT vs patients with PE)
Design
Multicenter prospective observational cohort study
Follow-up
Median of 21.3 months
Authors
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Supports low recurrence and bleeding with rivaroxaban in Japanese VTE; leaves open need for randomized confirmation.
Does rivaroxaban prevent recurrence or aggravation of symptomatic VTE in Japanese patients with venous thromboembolism?
In Japanese clinical practice, rivaroxaban demonstrated effectiveness and safety for treating a broad range of VTE patients, with low rates of recurrence and major bleeding.
Okumura et al. (2020) studied this question.
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