June 26, 2015AIDS Research and Human RetrovirusesOpen Access

Obesity Is Associated with Race/Sex Disparities in Diabetes and Hypertension Prevalence, But Not Cardiovascular Disease, Among HIV-Infected Adults

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Why the study?

Does obesity explain race/sex disparities in cardiometabolic disease prevalence among HIV-infected adults?

Structured PICO

Does obesity explain race/sex disparities in cardiometabolic disease prevalence among HIV-infected adults?

Population

1,800 HIV-infected adults (≥19 years old, white or African American) receiving care at the University of Alabama at Birmingham HIV clinic between July 2010 and June 2011, mean age 44.3, 77% male, 54% black.

Intervention

Obesity (BMI ≥30 kg/m²) and race/sex categories (black men, black women, white women)

Comparator

Non-obese status and white men (referent group)

Outcome

Prevalence of cardiometabolic diseases (dyslipidemia, cardiovascular disorders, hypertension, diabetes, chronic kidney disease)

Obesity explains the increased prevalence of diabetes and hypertension among HIV-infected black women, highlighting the need for targeted weight reduction interventions in this high-risk group.

Limitations

Lack of lifetime BMI records to account for changes in weight status
Inability to account for specific body morphology disorders such as lipoatrophy and lipohypertrophy
Lack of objective data on dietary intake and physical activity
Single geographic region (Southeastern United States) may limit generalizability
Reliance on EMR diagnosis history without fasting laboratory values

Discussion

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Implication

Obesity may mediate diabetes and hypertension disparities in HIV-infected black women; leaves open independent race/sex effects on other cardiometabolic outcomes.

Cite This Study

Willig et al. (2015) studied this question.

synapsesocial.com/papers/6a8261e80ebbaf848246c85d https://doi.org/10.1089/aid.2015.0062

Topics

Hypertension management Women and heart disease

View Full Paper

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Implication

Obesity may mediate diabetes and hypertension disparities in HIV-infected black women; leaves open independent race/sex effects on other cardiometabolic outcomes.

Obesity Is Associated with Race/Sex Disparities in Diabetes and Hypertension Prevalence, But Not Cardiovascular Disease, Among HIV-Infected Adults

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

Obesity Is Associated with Race/Sex Disparities in Diabetes and Hypertension Prevalence, But Not Cardiovascular Disease, Among HIV-Infected Adults

Structured PICO

Limitations

Discussion

Implication

Cite This Study

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