Maillard Reaction Products from 3-Deoxyglucosone and Butylamine under Physiological Conditions.

Acetic acid, N-butylacetamide, N-butyl-2-formyl-5-(hydroxymethyl)pyrrole, and N-butylformamide were formed as major compounds in a butylamine and 3-deoxyglucosone (3DG) reaction system under physiological conditions of 50°C at pH 7.4. N-Butylformamide is postulated to be formed by the cleavage of the C-C bond in α-dicarbonyl groups with the addition of amino compounds. Carbon at the 6 position in 3DG is speculated to be principally converted into methyl carbons of N-butylacetamide and acetic acid during the Maillard reaction.