Why the study?
Does electric field induced wave emission from heterogeneities improve the control of chaos in the heart compared to current clinical methods?
Does electric field induced wave emission from heterogeneities improve the control of chaos in the heart compared to current clinical methods?
Electric field induced wave emission from heterogeneities offers a novel theoretical or experimental approach to controlling cardiac chaos (arrhythmias) by increasing the number of control sites.
May increase pacing sites for arrhythmia control in animals; leaves open clinical translation.
The effectiveness of chaos control in large systems increases with the number of control sites. We find that electric field induced wave emission from heterogeneities (WEH) in the heart gives a unique opportunity to have as many control sites as needed. The number of pacing sites grows with the amplitude of the electric field. We demonstrate that WEH has important advantages over methods used in clinics, and opens a new way to manipulate vortices in experiments, and potentially to radically improve the clinical methods of chaos control in the heart.
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Pumir et al. (2007) studied this question.
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