Population
Isolated Ca2+-tolerant adult feline ventricular myocytes
Comparison
Ouabain (dose-dependent up to 10(-4) M) vs Absence of ouabain
Design
Preclinical
Authors
Loading...
Allows reliable K+ flux measurement in isolated feline myocytes; leaves open translation to human cardiac physiology.
This study demonstrates that transmembrane tracer kinetics and K+ fluxes can be reliably measured in isolated adult feline cardiac myocytes, allowing the identification of active and passive flux components using ouabain.
Silver et al. (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: