January 1, 1993European Heart Journal

A mechanism of cardiac pain suppression by spinal cord stimulation: implications for patients with angina pectoris

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Population

28 spinothalamic tract neurons recorded in anaesthetized monkeys

Design

Preclinical

Authors

MCMargaret J. ChandlerUniversity of Oklahoma Health Sciences Center TBTimothy J. BrennanBrigham Young University DGDavid W. GarrisonSoutheastern Oklahoma State University

Discussion

Member takes

Implication

Supports a spinal mechanism for SCS in angina; leaves open clinical translation from this animal model.

Structured PICO

Population

28 spinothalamic tract neurons recorded in anaesthetized monkeys

Intervention

Dorsal column stimulation

Outcome

Activity of spinothalamic tract neurons evoked by cardiac stimuli (electrical stimulation of cardiopulmonary sympathetic afferent fibres or intracardiac injection of bradykinin)surrogate

Dorsal column stimulation inhibits spinothalamic tract neurons activated by cardiac afferents, providing a neural mechanism for the relief of angina pectoris by spinal cord stimulation.

Cite This Study

Chandler et al. (1993) studied this question.

synapsesocial.com/papers/6a826d36f2e4e6540e2a58e7 https://doi.org/10.1093/eurheartj/14.1.96

View Full Paper

Ask AI

Bookmark

A mechanism of cardiac pain suppression by spinal cord stimulation: implications for patients with angina pectoris

Discussion

Member takes

Implication

Structured PICO

Cite This Study

A mechanism of cardiac pain suppression by spinal cord stimulation: implications for patients with angina pectoris

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider