Why the study?
Does propofol improve recovery compared to thiopentone in patients presenting for day-case dilatation and curettage?
Does propofol improve recovery compared to thiopentone in patients presenting for day-case dilatation and curettage?
Propofol provides superior early recovery of cognitive function and subjective alertness compared to thiopentone for day-case anesthesia.
This is the authors' abstract. We don't add key points for this paper.
Sixty patients who presented for day-case dilatation and curettage were allocated randomly to receive either thiopentone or propofol for induction and maintenance of anaesthesia. One anaesthetist administered all the anaesthetics whilst all assessments were made by one other. The results indicate that early recovery of memory function, critical flicker fusion frequency and subjective feelings of tiredness, drowsiness and alertness were superior in the propofol group. There was a significant difference in subjective feelings of tiredness and drowsiness recorded by the two study groups at 24 hours. Memory function assessed by Wechsler logical memory function passages at 24 hours was impaired in the propofol group in comparison to a group of 'reference' subjects.
Answers are grounded in this paper and cite their sources.
Propofol may be preferred over thiopentone for day-case D&C to hasten recovery; extends RCT evidence favoring its use in ambulatory anesthesia.
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Heath et al. (1990) studied this question.
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