Why the study?
Does intravenous terbutaline alter heart rate and blood pressure dynamics in healthy subjects at rest?
Population
Healthy subjects at rest
Comparison
Intravenous terbutaline vs Placebo
Design
RCT, randomized crossover, placebo-controlled
Authors
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Terbutaline disrupts baroreflex synchrony between R-R interval and blood pressure; extends mechanistic insight into autonomic control in healthy subjects.
Does intravenous terbutaline alter heart rate and blood pressure dynamics in healthy subjects at rest?
Nonlinear biosignal analysis reveals that terbutaline-induced modification of the baroreflex feedback loop causes R-R interval and systolic blood pressure to lose mutual synchrony.
Kuusela et al. (2002) studied this question.
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