Why the study?
Does an ultrasound protocol prevent renal ischemia-reperfusion injury in a mouse model of AKI?
Population
Anesthetized mice (model for human acute kidney injury)
Comparison
Ultrasound protocol administered 24 hours before… vs Sham treatment
Design
Preclinical
Follow-up
24 hours of reperfusion
Authors
Loading...
Supports ultrasound preconditioning for AKI prevention in preclinical models; hypothesis-generating with no clinical implications yet.
Does an ultrasound protocol prevent renal ischemia-reperfusion injury in a mouse model of AKI?
Pre-treatment with ultrasound preserves kidney function and morphology in a mouse model of renal ischemia-reperfusion injury by stimulating a splenic cholinergic anti-inflammatory pathway.
Gigliotti et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: