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October 1, 1992Journal of Biological ChemistryOpen Access

Tetanus toxin and botulinum toxins type A and B inhibit glutamate, gamma-aminobutyric acid, aspartate, and met-enkephalin release from synaptosomes. Clues to the locus of action.

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Authors

HMHarvey T. McMahonMRC Laboratory of Molecular BiologyPFPatrick ForanDefence Science and Technology LaboratoryJDJ. Oliver DollyDublin City University

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Cite This Study

McMahon et al. (1992) studied this question.

synapsesocial.com/papers/6a828e875b7acbbacb8d5abchttps://doi.org/10.1016/s0021-9258(19)36614-1
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia1991 · 52 citations
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  3. 3Affinity purified tetanus toxin binds to isolated chromaffin granules and inhibits catecholamine release in digitonin‐permeabilized chromaffin cells1989 · 16 citations
  4. 4Calcium transport and proton electrochemical potential gradient in mitochondria from guinea-pig cerebral cortex and rat heart1978 · 265 citations