Why the study?
Does prolonged exhaustive submaximal exercise impair muscle Na+-K+-ATPase activity and sarcoplasmic reticulum Ca2+ regulation in healthy subjects?
Population
8 healthy subjects with maximal O2 uptake of 3.93 +/- 0.69 l/min
Comparison
Cycling exercise at 74.3 +/- 1.2% maximal O2… vs Rest (baseline measurements)
Design
Other
Follow-up
Until fatigue (mean 72.18 +/- 6.46 min)
Authors
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May contribute to fatigue during exhaustive exercise; hypothesis-generating for Na+-K+-ATPase and SR Ca2+ roles in performance limitation.
Does prolonged exhaustive submaximal exercise impair muscle Na+-K+-ATPase activity and sarcoplasmic reticulum Ca2+ regulation in healthy subjects?
Prolonged exhaustive exercise acutely downregulates muscle Na+, K+, and Ca2+ transport processes, which may be important factors in fatigue.
Leppik et al. (2004) studied this question.
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