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April 1, 2000HeartOpen Access

Protecting the ischaemic and reperfused myocardium in acute myocardial infarction: distant dream or near reality?

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DYDerek M. Yellon

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Overview

Cardioprotection remains an unmet need in acute MI; leaves open validation of molecular targets in prospective trials.

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Cite This Study

Derek M. Yellon (2000) studied this question.

synapsesocial.com/papers/6a828f3aaa66c98ddba0bf2ehttps://doi.org/10.1136/heart.83.4.381
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart1997 · 132 citations
  2. 2Cardioprotection by opening of the KATPchannel in unstable angina Is this a clinical manifestation of myocardial preconditioning? Results of a randomized study with nicorandil1999 · 157 citations
  3. 3Dose-Dependent Reduction of Myocardial Infarct Mass in Rabbits by the NHE-1 Inhibitor Cariporide (HOE 642)1998 · 74 citations
  4. 4Thrombolysis in Acute Myocardial Infarction1993 · 180 citations
  5. 5Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia1997 · 108 citations