Why the study?
Does low-dose brain natriuretic peptide infusion alter central hemodynamics, cardiac function, renal hemodynamics, and microvascular hemodynamics in healthy subjects?
Does low-dose brain natriuretic peptide infusion alter central hemodynamics, cardiac function, renal hemodynamics, and microvascular hemodynamics in healthy subjects?
Low-dose BNP infusion in healthy subjects has predominantly central and renal hemodynamic effects without influencing peripheral microcirculation.
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Low-dose BNP shows compartment-specific central/renal effects without microvascular impact in healthy subjects; extends physiological mapping to guide patient-focused trials.
Zander et al. (2003) studied this question.
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