Key points are not available for this paper at this time.
Answers are grounded in this paper and cite their sources.
May refine spark models in skeletal muscle; leaves open extension to mammalian cardiac EC coupling.
Calcium sparks are brief, highly localized elevations of [Ca2+], which arise spontaneously or can be evoked by depolarization in many types of muscle cells. The Ca2+ is released into the cytoplasm from intracellular stores (the SR) through the SR Ca2+ release channels (the RYR). Since their
No takes yet. Share an insight, caveat, or question.
Withrow Gil Wier (2001) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: