Why the study?
Mediastinal radiation-induced severe calcific valve disease carries increased operative mortality, and transcatheter therapies are challenging and potentially hazardous.
Demonstrates the feasibility of using advanced imaging and planning technologies to successfully perform simultaneous TAVR and ViMAC in a high-risk patient with radiation-induced severe calcific valve disease.
May support combined TAVR and mitral valve-in-MAC in select high-risk patients; leaves open need for prospective validation.
Mediastinal radiation-induced severe calcific valve disease carries increased operative mortality. Transcatheter therapies are also challenging and potentially hazardous. We used a unique constellation of imaging and planning technologies to successfully plan, simulate, and perform novel combined transcatheter aortic valve replacement and valve in mitral annular calcification in a high-risk patient. (Level of Difficulty: Advanced.)
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Allen et al. (2020) studied this question.
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