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September 1, 1989Scandinavian Journal of Clinical and Laboratory Investigation

Characteristics of Doppler blood-velocity waveforms in a cardiovascular in vitro model. I. The model and the influence of pulse rate

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Why the study?

Does pulse rate influence Doppler flow-velocity curve indices in a cardiovascular in vitro model?

Population

Cardiovascular in vitro model consisting of a heart simulator and a circulatory system made of elastic butyl…

Comparison

Variation of pulse rate (PR) vs Constant pressure, volumetric flow, and…

Design

Preclinical

Authors

JLJesper LegarthHerlev HospitalETE. ThorupCopenhagen University Hospital

Discussion

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Implication

Pulse rate may confound Doppler index interpretation; leaves open need for in vivo validation before clinical adjustment.

Structured PICO

Does pulse rate influence Doppler flow-velocity curve indices in a cardiovascular in vitro model?

P
Population
Cardiovascular in vitro model consisting of a heart simulator and a circulatory system made of elastic butyl rubber tubes
I
Intervention
Variation of pulse rate (PR)
C
Comparator
Constant pressure, volumetric flow, and peripheral resistances
O
Outcome
Flow-velocity curve indices (pulsatility index [PI], peak velocity [Vpeak], rising slope [RS], and A/B ratio)surrogate

In an in vitro cardiovascular model, Doppler flow-velocity indices are significantly influenced by pulse rate, suggesting that pulse rate must be accounted for during clinical interpretation of these indices.

Cite This Study

Legarth et al. (1989) studied this question.

synapsesocial.com/papers/6a829a40e41271e79b8d5bd7https://doi.org/10.3109/00365518909089121
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characteristics of Doppler blood-velocity waveforms in a cardiovascular in vitro model. I. The model and the influence of pulse rate1989 · 23 citations
  2. 2Characteristics of Doppler blood-velocity waveforms in a cardiovascular in vitro model. II. The influence of peripheral resistance, perfusion pressure and blood flow1989 · 65 citations
  3. 3Evaluation of factors influencing arterial Doppler waveforms in an in vitro flow phantom2016 · 20 citations
  4. 4Evaluation of Blood Flow Velocity Waveform in an Animal Model1990 · 9 citations
  5. 5Vascular characteristics influence the aortic ultrasound Doppler signal: computer and hydraulic model simulations1993 · 5 citations