Population
Segments of human saphenous vein and internal mammary artery obtained from the same patient
Comparison
Organ culture in the presence of interleukin-1… vs Organ culture in the absence of interleukin-1…
Design
Preclinical
Follow-up
48 hours
Authors
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May indicate COX-2 protection in CABG conduits; hypothesis-generating for inhibition effects in vivo.
COX-2 is induced in human saphenous vein and internal mammary artery during organ culture, suggesting a potential endogenous defense mechanism against endothelial damage during CABG preparation.
Bishop‐Bailey et al. (1997) studied this question.
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