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August 31, 2023Anaesthesiology Intensive TherapyOpen Access

Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue

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Why the study?

Epicardial adipose tissue has been extensively studied as a marker for major adverse cardiovascular events, warranting a review of its biological pathways, imaging modalities, and clinical prognostic utility.

Does epicardial adipose tissue (EAT) assessment predict major adverse cardiovascular events (MACE) in patients with heart disease and critically ill patients?

Design

Review

Authors

JWJeroen WalpotAntwerp University Hospital
Caroline M. Van De Heyning
Caroline M. Van De HeyningCardiac Imaging
Johan Bosmans
Johan BosmansInterventional / Structural Cardiology

Discussion

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Member takes

Overview

EAT imaging may refine MACE risk stratification in cardiac patients; leaves open its incremental value and need for prospective validation.

Structured PICO

Does epicardial adipose tissue (EAT) assessment predict major adverse cardiovascular events (MACE) in patients with heart disease and critically ill patients?

P
Population
Patients with heart disease and critically ill patients
I
Intervention
Assessment of epicardial adipose tissue (EAT) using imaging modalities (echocardiography, cardiac CT, and cardiac magnetic resonance)
O
Outcome
Prediction of major adverse cardiovascular events (MACE) and mortalitysurrogate

Epicardial adipose tissue measured by imaging modalities is a promising biomarker for predicting major adverse cardiovascular events across various cardiac conditions.

Cite This Study

Walpot et al. (2023) studied this question.

synapsesocial.com/papers/6a82a0e7e41271e79b8d5cdehttps://doi.org/10.5114/ait.2023.130922
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis2023 · 78 citations
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  3. 3Epicardial Fat from Echocardiography: A New Method for Visceral Adipose Tissue Prediction2003 · 782 citations
  4. 4Epicardial fat gene expression after aerobic exercise training in pigs with coronary atherosclerosis: relationship to visceral and subcutaneous fat2010 · 57 citations
  5. 5Epicardial Fat in the Maintenance of Cardiovascular Health2017 · 132 citations